Science
MECHANISM OF ACTION
Compared to conventional quercetin, EubioQuercetin™ more closely mirrors the natural form quercetin takes in plants — with rutinose still attached. This unique structure not only boosts solubility and bioavailability, but also delivers an added benefit: prebiotic activity.
Standard quercetin is broken down and partially absorbed in the small intestine. Because the rutinose in EubioQuercetin™ is non-digestible, it arrives at the large intestine intact — carrying the quercetin with it. There, beneficial gut bacteria cleave the rutinose, unlocking its prebiotic effects. Rutinose then nourishes good bacteria and helps strengthen the gut barrier.*
The Research
A soon-to-be published clinical study indicates EubioQuercetin™ has benefits for both physical and mental health.*1
GUT AND MICROBIOME HEALTH
EubioQuercetin™ boosted beneficial gut bacteria that produce short-chain fatty acids (SCFAs), which have been shown to improve:
Metabolic health*
Gut health*
Immune function*
EubioQuercetin™ also raised levels of another bacterial species that promotes acetic acid production, which:
Promotes blood sugar balance*
Stimulates the release of GLP-1*
Supports cardiovascular health*
Reduces oxidative stress*
Together, these actions make EubioQuercetin a promising ingredient for healthy weight support.*
In vitro research further suggests EubioQuercetin™ blocks the fat-digesting enzyme lipase, reducing fat absorption — further evidence of its potential role in weight management.*
MOOD SUPPORT AND COGNITIVE FUNCTION
The same upcoming clinical study found that EubioQuercetin™:
- Supported serotonin production by reducing the stress hormone cortisol, which inhibits serotonin.*
- Inhibited monoamine oxidase (MOA), the enzyme that breaks down the neurotransmitters serotonin, dopamine, and norepinephrine.*
- Protected existing neurons and stimulated the growth of new ones.*
These actions could protect cognition and uplift mood.*
ROS SUPPRESSION
In vitro research has shown that EubioQuercetin™ quenches reactive oxygen species far more effectively than other forms of quercetin or rutin. Compare their ORAC scores:
For comparison, vitamin C — well known for its antioxidant power — has an ORAC score of 3,200.
RESEARCH ON QUERCETIN
Additional studies highlight the wide-reaching potential of quercetin, especially when its bioavailability is enhanced. Research on quercetin disaccharide — the natural form and key component of EubioQuercetin™ — have found benefits for body and mind.*
Cardiovascular Markers
In an 8-week double-blind, placebo-controlled, crossover study with 49 participants, quercetin significantly reduced waist circumference and helped maintain triglycerides and systolic blood pressure already within a healthy range.*2
Cognitive Function and Mood
Onion-derived quercetin supported cognitive function and promoted positive mood in 70 elderly participants in a 24-week randomized, double-blind, placebo-controlled, parallel group study.*3
References
- Yamaguchi M. Human Clinical Study on the Effect of EubioQuercetin Intake on the Diversity of Colonic Microflora and the Behavior of Quercetin Metabolites in Blood. ALPS Pharmaceutical Ind. Co., Ltd; 2024.
- Pfeuffer M, Auinger A, Bley U, et al. Effect of quercetin on traits of the metabolic syndrome, endothelial function and inflammation in men with different APOE isoforms. Nutr Metab Cardiovasc Dis NMCD. 2013;23(5):403-409. doi:10.1016/j.numecd.2011.08.010
- Nishihira J, Nishimura M, Kurimoto M, et al. The effect of 24-week continuous intake of quercetin-rich onion on age-related cognitive decline in healthy elderly people: a randomized, double-blind, placebo-controlled, parallel-group comparative clinical trial. J Clin Biochem Nutr. 2021;69(2):203-215. doi:10.3164/jcbn.21-17
LOW DOSAGE
125mg/day
STATUS
FUNCTIONS
MANAGEMENT
DELIVERY FORMATS
